Anesthetic Agent

There are 2 kind of anesthetic induction agents, inhalation and intravenous agents. The inhalation agents are halothan, sevoflurane, enflurane, isoflurane, and desflurane. For induction, we usually use sevoflurane, that rapid onset for induction and halothan (but this agent is hepatotoxic, so the use of this agent should not repeated until minimally 6 month). The others are not common for induction because they are irritant for the airway, and slow onset. Isoflurane is the best for use in neuroanesthesia, because of the neuroprotectif feature and less toxic on renal system. Enflurane has epileptogenic effect, so it must be avoid for use on epileptic patients. The intravenous agents are barbiturat (pentothal), propofol, etomidat, ketamin, and benzodiasepin (midazolam). The features of them are same except ketamin because it has simpatetic effect, not depressed the cardiovascular system, and has broncodilator feature. Pentothal has neuroprotectif feature, so it is the best for use in neuroanesthesia. Propofol has rapid onset and short duration, but must be careful to use it because can depress cardiovasculer system. Etomidat and benzodiazepin are more safe in patient with cardiovascular compromized, but benzodiazepin has slower onset.